CJC-1295 with DAC 5mg — GHRH Analogue Research Peptide

CJC-1295 with DAC 5mg is a synthetic growth hormone-releasing hormone (GHRH) analogue supplied by PeakForce Labs for laboratory research applications. This modified peptide incorporates a Drug Affinity Complex (DAC), providing researchers with a molecular platform for investigating albumin-associated peptide binding, GHRH receptor signaling, growth-hormone-associated pathways, and extended-duration peptide pharmacology.

Each vial contains 5mg of lyophilized CJC-1295 with DAC supplied in a sealed glass vial and independently verified through rigorous third-party analytical testing and applicable quality-control procedures.

Product Specifications

Compound: CJC-1295 with DAC

Research Classification: Modified GHRH analogue research peptide

Peptide Class: Growth hormone-releasing hormone receptor (GHRHR) agonist

Modification: Drug Affinity Complex (DAC)

Form: Lyophilized powder

Vial Configuration: 5mg supplied in a sealed glass vial

Purity: ≥99% where confirmed by applicable batch-specific analytical testing (See COA)

Appearance: White to off-white lyophilized material

Testing: Independent third-party analytical verification protocol

Analytical Verification

Every applicable batch of CJC-1295 with DAC undergoes analytical testing designed to support peptide identity, purity, content, and consistency.

Identity Verification: Confirms that the research material corresponds to the specified CJC-1295 with DAC peptide.

Purity Quantification: HPLC analysis evaluates target peptide relative to applicable impurities and synthesis-related byproducts.

Net Peptide Content: Confirms the applicable quantity of peptide material within the vial.

Visual Appearance: Confirms physical consistency of the lyophilized material against established product specifications.

Mass Spectrometry / Molecular Weight: Evaluates molecular characteristics to support peptide identity and chemical composition.

Batch Documentation: Analytical results are documented through applicable batch-specific COAs.

Research Context

CJC-1295 with DAC is a modified analogue of growth hormone-releasing hormone developed for research involving GHRH receptor signaling and extended-duration peptide behavior.

GHRH-associated peptides interact with the growth hormone-releasing hormone receptor (GHRHR), a class B G protein-coupled receptor expressed within relevant pituitary-associated cellular systems.

The addition of DAC distinguishes this research compound from shorter-acting GHRH analogues and provides a framework for investigating how molecular modification can influence peptide-protein interactions and pharmacokinetic characteristics.

Drug Affinity Complex (DAC) Research

The defining feature of CJC-1295 with DAC is its Drug Affinity Complex modification.

DAC technology was developed to facilitate covalent binding to circulating albumin through reactive functional groups associated with the peptide modification.

Albumin association has been investigated as a mechanism capable of substantially altering the circulating persistence and pharmacokinetic profile of peptide molecules.

This makes CJC-1295 with DAC particularly relevant to laboratory research examining:

• Peptide-albumin interactions
• Molecular modification strategies
• Extended-duration peptide pharmacology
• Peptide stability and disposition
• Relationships between molecular structure and pharmacokinetic behavior

These characteristics distinguish CJC-1295 with DAC from CJC-1295 without DAC and other shorter-duration GHRH-associated research peptides.

GHRH Receptor Signaling

The growth hormone-releasing hormone receptor belongs to the class B family of G protein-coupled receptors.

Activation of GHRHR is associated with Gs-protein signaling, adenylate cyclase activity, intracellular cyclic AMP (cAMP), and downstream protein kinase A-associated signaling.

CJC-1295 with DAC provides researchers with a molecular tool for investigating these receptor-mediated processes in appropriate laboratory systems.

Growth Hormone-Associated Research

GHRH receptor signaling is closely associated with growth-hormone-related neuroendocrine biology.

CJC-1295 with DAC has therefore been investigated in experimental systems examining relationships among GHRH receptor activation, pituitary-associated signaling, growth-hormone-associated pathways, and downstream signaling networks.

The extended pharmacokinetic characteristics associated with the DAC modification also provide a framework for comparing sustained and shorter-duration GHRH receptor signaling.

This research context does not establish increased growth hormone as a desirable outcome or imply therapeutic, performance-enhancing, or physiological benefits.

GH/IGF-1 Axis Research

Growth-hormone-associated signaling is functionally connected with insulin-like growth factor-1 (IGF-1)-associated pathways.

Research involving GHRH analogues can therefore provide insight into relationships among GHRHR activation, growth-hormone-associated signaling, IGF-1-associated pathways, and downstream cellular responses.

These experimental relationships provide a biochemical research framework and do not establish muscle growth, tissue regeneration, fat reduction, improved body composition, or other physiological outcomes.

Metabolic Signaling Research

Growth-hormone-associated pathways intersect with multiple areas of cellular metabolism.

Experimental systems involving CJC-1295 with DAC may therefore examine relationships among GHRH receptor signaling, lipid-associated metabolism, glucose-associated cellular processes, substrate utilization, and metabolic gene-expression pathways.

Such research does not establish metabolic optimization, weight reduction, increased energy expenditure, or improved insulin sensitivity.

Peptide Engineering Research

CJC-1295 with DAC is also relevant to peptide-engineering research because its molecular modification was specifically designed to alter interactions between the peptide and circulating proteins.

This provides researchers with an opportunity to investigate how peptide modifications can influence:

• Protein binding
• Molecular stability
• Peptide disposition
• Receptor-signaling duration
• Pharmacokinetic behavior
• Structure-function relationships

CJC-1295 with DAC 5mg is intended solely for in vitro research and laboratory investigation by qualified personnel in appropriate research environments.

CJC-1295 with DAC vs. CJC-1295 without DAC

CJC-1295 with DAC and CJC-1295 without DAC are distinct research materials and should not be treated as interchangeable compounds.

CJC-1295 with DAC incorporates a Drug Affinity Complex designed to facilitate albumin association and is investigated in connection with extended-duration peptide behavior.

CJC-1295 without DAC lacks this albumin-binding modification and is investigated as a shorter-duration GHRH-associated research peptide.

This structural distinction makes the two compounds useful for different experimental questions involving peptide modification, receptor signaling, and pharmacokinetic behavior.

Reconstitution and Storage

Lyophilized storage: Store sealed in a cool, dry location away from direct light

Long-term storage: -20°C for maximum stability where consistent with product-specific stability documentation

Post-reconstitution: Once reconstituted for research purposes, store reconstituted material at 2-8°C and protect from light

Reconstituted use window: Within 60 days for optimal research integrity where supported by product-specific stability documentation

Avoid: Repeated freeze-thaw cycles to preserve peptide stability and structural integrity

Quality Assurance

PeakForce Labs maintains rigorous quality-control standards across its research compounds. Our quality assurance procedures emphasize analytical verification, consistency, and traceability:

• Independent third-party analytical testing on applicable batches
• Peptide identity verification
• HPLC purity analysis
• Mass spectrometry verification where applicable
• Net peptide content verification
• Heavy metal screening where applicable
• Full product traceability
• Batch-specific COAs
• Same-day shipping available for orders placed before daily 3PM CST cutoff

Terms of Sale

By purchasing this product, the buyer confirms and attests that:

• They are 21 years of age or older
• They are a qualified research professional, authorized research personnel, or research institution
• They accept full responsibility for proper handling, storage, and use of this material in accordance with all applicable regulations
• They will not use this material for human consumption, veterinary use, or any in vivo application

About PeakForce Labs

PeakForce Labs is a Houston, Texas-founded research compound supplier specializing in high-quality research materials for laboratory applications. Our research products are supplied with an emphasis on analytical verification, product consistency, traceability, and quality assurance.

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