VIP 10mg — Vasoactive Intestinal Peptide Research Peptide

VIP 10mg is a synthetic Vasoactive Intestinal Peptide research material supplied by PeakForce Labs for laboratory research applications. VIP is a naturally occurring 28-amino-acid neuropeptide investigated across neuroendocrine, gastrointestinal, vascular, pulmonary, and immune-associated signaling systems.

VIP interacts primarily with VPAC1 and VPAC2 receptors, members of the class B G protein-coupled receptor (GPCR) family. Each vial contains 10mg of lyophilized VIP supplied in a sealed glass vial and independently verified through rigorous third-party analytical testing.

Product Specifications

Compound: VIP (Vasoactive Intestinal Peptide)

Research Classification: Synthetic neuropeptide / peptide signaling research compound

Primary Research Targets: VPAC1 and VPAC2 receptors

Amino Acid Length: 28 amino acids

Amino Acid Sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂

Molecular Formula: C₁₄₇H₂₃₇N₄₃O₄₂S

Molecular Weight: Approximately 3326.77 g/mol

Form: Lyophilized powder

Vial Configuration: 10mg supplied in a sealed glass vial

Purity: ≥98% HPLC verified, with exact analytical results provided on the applicable batch-specific COA

Appearance: White to off-white powder

Testing: Independent third-party analytical verification protocol

Analytical Verification

Every applicable batch of VIP undergoes analytical testing designed to support peptide identity, purity, content, and consistency.

Identity Verification: Confirms that the research material corresponds to Vasoactive Intestinal Peptide.

Purity Quantification: HPLC analysis evaluates target peptide relative to applicable impurities and synthesis-related byproducts.

Net Peptide Content: Confirms the applicable quantity of peptide material within the vial.

Visual Appearance: Confirms physical consistency of the lyophilized material against established product specifications.

Mass Spectrometry / Molecular Weight: Evaluates molecular characteristics to support peptide identity and chemical composition.

Batch Documentation: Analytical results are documented through applicable batch-specific COAs.

Research Context

Vasoactive Intestinal Peptide is a 28-amino-acid neuropeptide investigated as a signaling molecule across multiple biological systems.

VIP belongs to the secretin/glucagon family of peptide signaling molecules and is studied primarily through its interactions with VPAC1 and VPAC2 receptors.

VPAC1 and VPAC2 Receptor Signaling

VPAC1 and VPAC2 are class B G protein-coupled receptors expressed across numerous cellular systems.

VIP binding to these receptors is associated with activation of intracellular second-messenger pathways, particularly cyclic adenosine monophosphate (cAMP)-associated signaling.

This receptor profile provides researchers with a defined framework for examining ligand-receptor interactions, GPCR pharmacology, second-messenger activity, and downstream cellular signaling.

Neuroendocrine Signaling Research

VIP is investigated extensively within neurobiological and neuroendocrine research.

Experimental models involving VIP provide opportunities to examine neuronal signaling, neuropeptide-receptor interactions, neurotransmitter-associated systems, and communication between neuronal and endocrine-associated cellular pathways.

Immune-Associated Cellular Research

VIP and its receptors are also investigated in immune-associated cellular systems.

Laboratory research has examined relationships between VIP-receptor signaling and cytokine-associated pathways, transcriptional responses, immune-cell signaling, and other components of cellular communication.

These areas of investigation describe molecular signaling relationships and do not establish anti-inflammatory, immunosuppressive, or therapeutic effects.

Gastrointestinal Research

VIP was originally identified in gastrointestinal-associated research and remains an important neuropeptide for investigating signaling within gastrointestinal cellular systems.

Experimental investigation includes receptor signaling, epithelial-associated biology, enteric neuronal communication, and smooth-muscle-associated cellular pathways.

Vascular and Smooth-Muscle Signaling

VIP receptor activity is also investigated in vascular and smooth-muscle-associated experimental systems.

These models provide researchers with a framework for examining GPCR signaling, intracellular cAMP pathways, cellular contractility-associated signaling, and interactions between neuropeptides and smooth-muscle cells.

Pulmonary-Associated Research

VIP and VPAC receptors are expressed within pulmonary-associated cellular systems and have been investigated in experimental models involving airway biology, epithelial signaling, smooth-muscle-associated pathways, and neuroimmune communication.

These studies provide a molecular research context and do not establish respiratory, vascular, or therapeutic outcomes.

VIP 10mg is intended solely for in vitro research and laboratory investigation by qualified personnel in appropriate research environments.

Reconstitution and Storage

Lyophilized storage: Store sealed in a cool, dry location away from direct light

Long-term storage: -20°C for maximum stability where consistent with product-specific stability documentation

Post-reconstitution: Once reconstituted for research purposes, store reconstituted material at 2-8°C and protect from light

Reconstituted use window: Within 60 days for optimal research integrity where supported by product-specific stability documentation

Avoid: Repeated freeze-thaw cycles to preserve peptide stability and structural integrity

Quality Assurance

PeakForce Labs maintains rigorous quality-control standards across its research compounds. Our quality assurance procedures emphasize analytical verification, consistency, and traceability:

• Independent third-party analytical testing on applicable batches
• Peptide identity verification
• HPLC purity analysis
• Mass spectrometry verification where applicable
• Net peptide content verification
• Heavy metal screening where applicable
• Full product traceability
• Batch-specific COAs
• Same-day shipping available for orders placed before daily 3PM CST cutoff

Terms of Sale

By purchasing this product, the buyer confirms and attests that:

• They are 21 years of age or older
• They are a qualified research professional, authorized research personnel, or research institution
• They accept full responsibility for proper handling, storage, and use of this material in accordance with all applicable regulations
• They will not use this material for human consumption, veterinary use, or any in vivo application

About PeakForce Labs

PeakForce Labs is a Houston, Texas-founded research compound supplier specializing in high-quality research materials for laboratory applications. Our research products are supplied with an emphasis on analytical verification, product consistency, traceability, and quality assurance.

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