TB-500 10mg — Thymosin Beta-4 Research Peptide

TB-500 10mg is a synthetic Thymosin Beta-4-associated research peptide supplied by PeakForce Labs for laboratory research applications. Thymosin Beta-4 (Tβ4) is a naturally occurring 43-amino-acid peptide extensively investigated for its interactions with actin and its role in cytoskeletal organization and cell-migration-associated processes.

Each vial contains 10mg of lyophilized research peptide supplied in a sealed glass vial and independently verified through rigorous third-party analytical testing.

Product Specifications

Compound: TB-500 / Thymosin Beta-4-associated research peptide

Research Classification: Synthetic actin-binding research peptide

Primary Research Interaction: G-actin binding and cytoskeletal-associated processes

Amino Acid Length: 43 amino acids, where confirmed by batch-specific documentation

Amino Acid Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser

Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S

Molecular Weight: Approximately 4963.44 g/mol

Form: Lyophilized powder

Vial Configuration: 10mg supplied in a sealed glass vial

Purity: ≥98% HPLC verified, with exact analytical results provided on the applicable batch-specific COA

Appearance: White to off-white powder

Testing: Independent third-party analytical verification protocol

Analytical Verification

Every applicable batch of TB-500 undergoes analytical testing designed to support peptide identity, purity, content, and consistency.

Identity Verification: Confirms that the research material corresponds to the specified peptide.

Purity Quantification: HPLC analysis evaluates target peptide relative to applicable impurities and synthesis-related byproducts.

Net Peptide Content: Confirms the applicable quantity of peptide material within the vial.

Visual Appearance: Confirms physical consistency of the lyophilized material against established product specifications.

Mass Spectrometry / Molecular Weight: Evaluates molecular characteristics to support peptide identity and chemical composition.

Batch Documentation: Analytical results are documented through applicable batch-specific COAs.

Research Context

Thymosin Beta-4 is a naturally occurring peptide investigated extensively in research involving actin dynamics, cytoskeletal organization, cell migration, and related cellular processes.

A central biochemical characteristic of Thymosin Beta-4 is its interaction with monomeric globular actin (G-actin), making it an important research tool for studying the regulation of cellular actin pools.

Actin-Binding Research

Actin is a highly conserved cellular protein involved in cytoskeletal structure, cellular morphology, migration, adhesion, and numerous intracellular processes.

Thymosin Beta-4 interacts with G-actin and participates in regulation of the balance between monomeric and polymerized actin.

Experimental investigation of this interaction provides researchers with a framework for examining actin dynamics and cytoskeletal-associated cellular processes.

Cellular Migration

Dynamic remodeling of the actin cytoskeleton is fundamental to cell migration.

Thymosin Beta-4-associated research has therefore examined cellular systems involving migration, cytoskeletal rearrangement, cell adhesion, and morphological changes.

These experimental systems may include fibroblast, epithelial, endothelial, and other cell types used to investigate migration-associated molecular mechanisms.

Endothelial Cell Research

Thymosin Beta-4 has been investigated in endothelial-associated cellular models involving migration, cytoskeletal organization, and signaling pathways associated with vascular cell biology.

These systems provide a framework for examining relationships among actin regulation, endothelial cellular behavior, and angiogenesis-associated molecular processes without establishing vascular or therapeutic outcomes.

Extracellular Matrix and Cellular Remodeling Research

Cytoskeletal organization and cell migration interact closely with extracellular-matrix-associated processes.

Research involving Thymosin Beta-4 provides opportunities to investigate relationships among actin dynamics, cellular migration, extracellular matrix interactions, and cellular remodeling-associated signaling.

Cellular Stress and Signaling Research

Thymosin Beta-4 has also been investigated across experimental systems involving cellular stress responses, transcriptional signaling, chemokine-associated pathways, and cell-survival-associated molecular processes.

These areas of research describe experimental molecular relationships and do not establish anti-inflammatory, cytoprotective, regenerative, cardiac, or therapeutic effects.

TB-500 10mg is intended solely for in vitro research and laboratory investigation by qualified personnel in appropriate research environments.

Reconstitution and Storage

Lyophilized storage: Store sealed in a cool, dry location away from direct light

Long-term storage: -20°C for maximum stability where consistent with product-specific stability documentation

Post-reconstitution: Once reconstituted for research purposes, store reconstituted material at 2-8°C and protect from light

Reconstituted use window: Within 60 days for optimal research integrity where supported by product-specific stability documentation

Avoid: Repeated freeze-thaw cycles to preserve peptide stability and structural integrity

Quality Assurance

PeakForce Labs maintains rigorous quality-control standards across its research compounds. Our quality assurance procedures emphasize analytical verification, consistency, and traceability:

• Independent third-party analytical testing on applicable batches
• Peptide identity verification
• HPLC purity analysis
• Mass spectrometry verification where applicable
• Net peptide content verification
• Heavy metal screening where applicable
• Full product traceability
• Batch-specific COAs
• Same-day shipping available for orders placed before daily 3PM CST cutoff

Terms of Sale

By purchasing this product, the buyer confirms and attests that:

• They are 21 years of age or older
• They are a qualified research professional, authorized research personnel, or research institution
• They accept full responsibility for proper handling, storage, and use of this material in accordance with all applicable regulations
• They will not use this material for human consumption, veterinary use, or any in vivo application

About PeakForce Labs

PeakForce Labs is a Houston, Texas-founded research compound supplier specializing in high-quality research materials for laboratory applications. Our research products are supplied with an emphasis on analytical verification, product consistency, traceability, and quality assurance.

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